Please join host Hiten Madhani in welcoming the next Biochem Basic Science Seminar special guest speaker of the series, Dr. Russell Vance, Professor and HHMI Investigator of Molecular and Cell Biology at University of California, Berkeley for his talk titled: "Mechanisms and Functions of Inflammasomes in Host Defense" via Zoom on Tuesday, November 17, 2020 at 12pm.
Abstract: Inflammasomes are multiprotein complexes that function as guardians of the cytosol of mammalian cells, responsible for the initial detection of pathogens and orchestration of downstream protective responses. Several inflammasomes are scaffolded by proteins of the nucleotide-binding domain leucine-rich repeat (NLR) superfamily. Surprisingly, our work has revealed that despite considerable structural homology, the molecular mechanisms by which different NLRs assemble into inflammasomes differ dramatically. In my seminar, I will discuss our latest insights into inflammasome mechanisms and functions.
To learn more, visit the Vance Lab, here.
ZOOM: CHECK EMAIL FOR DETAILS