The QBI Seminar Series is presenting Dr. Ali Shilatifard of Northwestern University on Tuesday, November 6, 2018, at 10:00 AM at Gladstone Institutes. Dr. Shilatifard is a professor, chairman of the department of biochemistry and molecular genetics, and the director of the Simpson Query Center for Epigenetics at the Northwestern University Feinberg School of Medicine. He has served as a senior editor for the journal Science, and currently serves as the Editor for Science's open access journal Science Advances.
Shilatifard's lab focuses on the cause of childhood leukemia through chromosomal translocations, the role of ELL in this process, and the discovery of the Super Elongation Complex as being a central complex linking MLL translocations into a diverse number of genes to leukemic pathogenesis. Dr. Shilatifard will discuss his laboratory’s latest biochemical and genetic studies defining the molecular properties of COMPASS and PcG families in the epigenetic regulation of gene expression, during development and during disease pathogenesis. He will also discuss their effort in taking advantage of basic molecular information in regard to epigenetic regulation of gene expression to develop targeted therapeutics for the treatment of hematological malignancies, pediatric brain cancer, and other forms of solid tumors.
Host: Nevan Krogan
Register: http://qbi.ucsf.edu/alishilatifard